Giants Wilmer Flores’ 3-run blast stuns Reds on Opening Day

Wilmer Flores, of the Giants, hits a tie-breaking, three-run home run against the Reds in the ninth inning on Thursday, March 27, 2025, on Opening Day at Great American Ball Park in Cincinnati. David Jablonski/Staff
2025.03.27 – Wilmer Flores hit a three-run blast with two outs in the ninth inning, and the San Francisco Giants stun the Cincinnati Reds with a 6-4 victory on MLB’s Opening Day at Great American Ball Park.
Flores was never himself last season. He injured his knee early. He tried to play through the pain. He ended up with the worst season of his career, one that ended with him undergoing season-ending Tenex procedure on his 33rd birthday.
Still, the Giants’ brass maintained faith. They believed that with a clean bill of health, Flores could get back to the form he exhibited in 2023, when he hit a career-high 23 homers. Thursday, that faith was rewarded.
One game does not make a season, but if for just a day, San Francisco’s conviction in Flores is paying dividends.
“He’s built for those moments,” said left fielder Heliot Ramos, the Giants’ 19th consecutive Opening Day outfielder in the last 19 years. “The fact that it was him was super cool to see, bouncing back from last year and all the injuries.”
Added manager Bob Melvin: “He’s usually better when there’s more money on the line.”
For there to be money on the line, the hitters ahead of Flores needed to cash in on their own trips to the plate.
2025.03.27 (Giants vs Reds) See Full Highlights

Wilmer Flores is greeted at home plate by Patrick Bailey, second from left, and Matt Chapman, after hitting a three-run homer in the 9th inning of an Opening Day game vs. the Cincinnati Reds on Thursday. Carolyn Kaster/Associated Press
2025.03.27 (Giants vs Reds) See Full Highlights
2025.03.27 (Giants vs Reds) See Full Highlights
The Giants entered the ninth inning trailing 3-2, their only offense to that point deriving from Ramos’ two-run, opposite-field home run in the top of the fourth off Hunter Greene. Aside from that swing, San Francisco’s offense was mostly flat. The Giants had struck out 14 times and mustered three hits to that point. But in the ninth, despite striking out three more times, the Giants’ offense showed signs of life.
Jung Hoo Lee set the table by drawing a one-out walk, then advanced to third on Matt Chapman’s single to right field. Ramos struck out, bringing the Giants down to their last out, but Patrick Bailey drove in Lee with a single just beyond the outstretched glove of second baseman Matt McLain. That brought up Flores.
Prior to the game, Flores told shortstop Willy Adames that he’d never hit a home run on Opening Day. With one swing, he crossed that off the bucket list.
Reds closer Ian Gibaut hung Flores a middle-middle sweeper, and Flores promptly sent it into the left-field bleachers. Not only did Flores give the Giants the lead, but he kicked off a cacophony of boos. The fan who caught Flores’ home run ball threw it back on the field with such vigor that the ball ended up in the infield, rolling past Cincinnati’s Elly De La Cruz.
“He’s always been a clutch guy,” Melvin said. “A lot of walk-offs in his career. The bigger the situation, the better he’s been.”
2025.03.27 – Giants vs Reds (NBC Sports Post Recap)

Thursday, March 27, 2025, San Francisco Giants vs. the Cincinnati Reds on Opening Day at Great American Ball Park in Cincinnati. David Jablonski/Staff
2025.03.27 – Giants vs Reds (NBC Sports Post Recap)
2025.03.27 – Giants vs Reds (NBC Sports Post Recap)
2025.03.27 – Giants vs Reds (Locked On Post Recap)

San Francisco Giants pitcher Logan Webb throws in the first inning Thursday, March 27, 2025 in Cincinnati. Carolyn Kaster/Associated Press
2025.03.27 – Giants vs Reds (Locked On Post Recap)
2025.03.27 – Giants vs Reds (Locked On Post Recap)
Ramos has historically struggled against right-handed pitchers, entering the day with a career .656 OPS against righties compared to .956 OPS against lefties. He’ll likely see time in leadoff when a left-hander is on the mound. Despite his struggles against righties, the 25-year-old invites the challenge.
“Lefties, I know I can hit them. Obviously, lefties are going to get me out. They’re pitchers, too. They eat, too,” Ramos said. “But I’ve been wanting to face righties. I’ve been wanting to make that a point, for sure.”
With those swings from Flores and Ramos, the team, as a whole, has made quite a point too.
The Giants enjoyed a great spring training. They went 21-6. They were third in ERA and OPS. They excelled in every facet of the game.
They believe they can make the playoffs. They believe they can make noise, even in a stacked NL West. A win on Opening Day, one that gives Buster Posey a 1-0 record as president of baseball operations, was a step in that direction.
UP NEXT
Giants: Right-hander Justin Verlander will make his San Francisco debut on Saturday.
Reds: Lefty Nick Lodolo will go for the Reds on Saturday.
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Read more at: San Francisco Giants Media Services / More AP MLB
JEstevez@EMIsportsCentral.com
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