49ers beat Dolphins with ‘Mr. Irrelevant’ Purdy

San Francisco 49ers’ QB2 Brock Purdy (Last pick in the NFL draft ‘Mr. Irrelevant’) passes against Miami Dolphins during Niners’ 33-17 win in NFL game at Levi’s Stadium in Santa Clara, Calif., on Sunday, December 4, 2022. Scott Strazzante / The Chronicle

2022.12.04 – Brock Purdy ‘Mr. Irrelevant’ (Last pick in the NFL draft) threw two touchdown passes after replacing Jimmy Garoppolo and the San Francisco 49ers used another dominant defensive performance to beat the Miami Dolphins 33-17 on Sunday for its fifth straight win.

The Dolphins hit San Francisco’s vaunted defense with a 75-yard haymaker on the opening play and then watched 49ers quarterback Garoppolo leave with a season-ending foot injury.

Everything was set up for another win for the streaking Dolphins, but backup quarterback Purdy and the Niners had other ideas.

“Guys were a little off, just in general collectively,” Dolphins coach Mike McDaniel said. “But I know one thing: It wasn’t because of preparation, lack of detail. It was one of those things that you have to go through.”

Tua Tagovailoa threw a 75-yard touchdown pass to Trent Sherfield on the opening play from scrimmage but struggled to do much else behind a patchwork line for Miami (8-4) against Nick Bosa and the Niners’ defense.

Purdy, dubbed “Mr. Irrelevant” as the last pick of this year’s NFL draft, proved to be quite important to the 49ers when Garoppolo broke his left foot on a sack on the final play of the opening drive.

Garoppolo was taken to the locker room on a cart and didn’t return, leaving the game in the hands of Purdy, who had thrown his only nine passes in mop-up duty of a Week 7 loss to Kansas City.

Purdy capped his first drive of the game by throwing a 3-yard TD pass to Kyle Juszczyk to give San Francisco a 10-7 lead.

He then led a well-executed two-minute drive at the end of the half, completing six passes for 75 yards with a 3-yard TD to Christian McCaffrey with 4 seconds left in the half to make it 17-10.

Purdy finished 25 for 37 for 210 yards, two TDs and one interception.

2022.12.04 – (SF 49ers vs. MIA Dolphins) NFL Video Highlights

San Francisco 49ers’ Brock Purdy passes in 2nd quarter against Miami Dolphins during NFL game at Levi’s Stadium in Santa Clara, Calif., on Sunday, December 4, 2022. Scott Strazzante / The Chronicle

2022.12.04 – (SF 49ers vs. MIA Dolphins) NFL Video Highlights

Tagovailoa, who came into the game with three interceptions on the season, threw two in the third quarter to Jimmie Ward and Deommodore Lenoir to lead to a pair of field goals for the 49ers (8-4).

“It sucks that we didn’t come out and say what we wanted to do collectively as a team,” Tagovailoa said. “Obviously, it starts with me offensively. Turnovers, with third-down communication errors, in that retrospect it’s hard to win a game when you’re not on your Ps and Qs and you’re not dialed in.”

The 49ers had their four-game, second-half shutout streak snapped when Tagovailoa threw a 45-yard TD pass to Tyreek Hill in the opening minute of the fourth quarter but held on from there. They capped the performance with a strip-sack from Bosa that Dre Greenlaw returned for a 23-yard score.

Bosa finished with three sacks, taking advantage of a line missing starting tackles Terron Armstead and Austin Jackson.

“We didn’t flinch,” 49ers linebacker Fred Warner said about the response to the opening play. “We came back to the sideline and you can’t look at things like that emotionally. You’ve got to just look at it for what it is and and see how you can adjust. I guess that kind of allowed us to really settle into the game quicker, obviously when you when you have a play like that.”

2022.12.04 – SF 49ers vs. MIA Dolphins (NBC Sports: Post-Game Show)

San Francisco 49ers’ Jimmy Garoppolo has his left foot caught under Miami Dolphins’ Jaelan Phillips in 1st quarter during NFL game at Levi’s Stadium in Santa Clara, Calif., on Sunday, December 4, 2022. Scott Strazzante / The Chronicle

2022.12.04 – SF 49ers vs. MIA Dolphins (NBC Sports Post Game Show)

Watch this video on YouTube

2022.12.04 – SF 49ers vs. MIA Dolphins (NBC Sports Post Game Show)

The Dolphins had their five-game winning streak snapped in coach McDaniel’s first game against the 49ers after spending the past five years as an assistant in San Francisco.

Garoppolo out for the season

The 49ers lost quarterback Garoppolo to a season-ending left foot injury Sunday, dealing a big blow to one of the NFL’s top teams.

Garoppolo got hurt on the opening drive and will need to undergo surgery that will sideline him for the remainder of the season.

“It’s pretty crushing. We know what Jimmy’s been through, how hard he’s worked at this,” coach Kyle Shanahan said. “That was a really cool game, just as a team and all the stuff that went on throughout the game and just be able to overcome some things. So it’s such a special win. But definitely mixed emotions hearing about Jimmy.”

The first-place 49ers (8-4) have won five straight games to establish themselves as one of the top contenders in the NFC but now must go the rest of the way with the untested rookie Purdy after losing starter Trey Lance to a season-ending ankle injury during a Seahawks game in Week 2.

This is the third time Garoppolo has had a season derailed by injury since joining the 49ers midway through the 2017 season. He went down with a season-ending knee injury in the third game of the 2018 season and missed eight games with ankle injuries in 2020.

“It’s brutal,” running back Christian McCaffrey said. “I haven’t been around a long time here, but I can’t say enough good things about him. I’ve been in that position before, where you’re playing and you’re excited and it all ends for the year. It hurts.”

CHALLENGE

Shanahan won two challenges in the fourth quarter to overturn completed passes by Miami. The second came on a fourth-and-2 play with the Niners leading by six with about six minutes left.

The Niners held the ball for nearly four minutes and made it a two-score game when Robbie Gould kicked a 48-yard field goal, his fourth of the day.

FAST START

The Dolphins wasted little time showing off their speed when Tagovailoa connected on the long touchdown to Sherfield on the first play from scrimmage.

It marked the first time a team scored on the first play after the opening kick since the Niners did it in Week 2 of the 2020 season against the Jets with an 80-yard run by Raheem Mostert.

The touchdown ended a scoreless streak of more than 94 minutes for the 49ers, who hadn’t allowed a point since the second quarter against Arizona two weeks ago.

Miami hadn’t scored a TD on the first play from scrimmage following the opening kick since the final game of the 2004 season when Sage Rosenfels threw a 76-yard pass to Chris Chambers against Baltimore.

2022.12.04 – SF 49ers vs. MIA Dolphins (KRUEGER: Post-Game Show)

San Francisco 49ers’ Nick Bosa rushes before sacking Miami Dolphins’ Tua Tagovailoa in 2nd quarter during NFL game at Levi’s Stadium in Santa Clara, Calif., on Sunday, December 4, 2022. Scott Strazzante / The Chronicle

2022.12.04 – SF 49ers vs. MIA Dolphins (KRUEGER: Post Game Show)

Watch this video on YouTube

2022.12.04 – SF 49ers vs. MIA Dolphins (KRUEGER: Post Game Show)

Now the Niners will try to go the rest of the way with Purdy, who came into the league as Mr. Irrelevant after being taken with the final draft pick but now has the most important job on one of the league’s top teams.

“I feel like there was a little just like, the whole butterfly feeling of ‘Man, we’re going in, let’s do this,’” Purdy said. “It wasn’t like I was out there like shaking like, ‘Oh, shoot, what do I do? What’s my read?’ None of that. Every single week I act like I’m the starter. I prepare like I’m the starter. My name was called. Coach Griese said let’s roll.”

INJURIES

Dolphins: WR Jaylen Waddle left in the first half with a leg injury but returned to the game.

49ers: The only other QB under contract is Jacob Eason, who is on the practice squad. … DT Hassan Ridgeway (pectoral) left in the fourth quarter and didn’t return.